Related Articles
International Journal of Pharmaceutics. 2007 Jun
Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes.
A novel method for encapsulating irinotecan into liposomes containing copper gluconate buffered to pH 7.0 with triethanolamine (TEA) has recently been developed. In the present study, the mechanism dictating drug encapsulation and retention inside those liposomes was investigated. Spectroscopic analyses revealed that irinotecan interacted with copper gluconate/TEA in solution. Fourier transformed infrared (FT-IR) spectroscopy indicated…
Bioresource Technology. 2010 Feb
Adsorption of copper-citrate complexes on chitosan: equilibrium modeling.
The effects of complexes on the adsorption of copper from citrate solutions using chitosan were investigated. Various copper to citrate ratios and solution pHs were used to determine the copper adsorption capacity on the chitosan and a mathematical model was developed to simulate the copper adsorption process. According to the model, the three parameters influencing…
Pnas. 2014 Jul
Excited-state structural dynamics of a dual-emission calmodulin-green fluorescent protein sensor for calcium ion imaging
Fluorescent proteins (FPs) have played a pivotal role in bioimaging and advancing biomedicine. The versatile fluorescence from engineered, genetically encodable FP variants greatly enhances cellular imaging capabilities, which are dictated by excited-state structural dynamics of the embedded chromophore inside the protein pocket. Visualization of the molecular choreography of the photoexcited chromophore requires a spectroscopic technique…
Nutrition Reviews. 2012 Jul
Role of calcium during pregnancy: maternal and fetal needs
Although the demand for additional calcium during pregnancy is recognized, the dietary reference intake for calcium was lowered for pregnant women in 1997 to amounts recommended for nonpregnant women (1,000 mg/day), and recently (November 2010) the Institute of Medicine report upheld the 1997 recommendation. It has been frequently reported that women of childbearing age do…
Journal of Internal Medicine. 2006 May
Calcium and vitamin D in the prevention and treatment of osteoporosis – a clinical update
Combined calcium and vitamin D supplementation is an essential component of the management of osteoporosis, supported by a strong scientific rationale. The types of individuals who should receive calcium and vitamin D supplements are those: (i) patients with documented osteoporosis receiving antiresorptive or anabolic treatment; (ii) patients receiving glucocorticoids; and (iii) individuals with or at…
Journal of Biological Chemistry. 2014 Apr
The plasma membrane calcium pump: new ways to look at an old enzyme.
The three-dimensional structure of the PMCA pump has not been solved, but its basic mechanistic properties are known to repeat those of the other Ca(2+) pumps. However, the pump also has unique properties. They concern essentially its numerous regulatory mechanisms, the most important of which is the autoinhibition by its C-terminal tail. Other regulatory mechanisms…
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2019 Mar
Traditional materials from new sources – conflicts in analytical methods for calcium carbonate.
Calcium carbonate (E170) is a common food and pharmaceutical additive/ingredient. In addition to a source of calcium, the carbonate has uses including as a colour, acidity regulator and bulking agent. Globally, a range of regulatory agencies and pharmacopoeia control the analyses and specification of additives in food, supplements, pharmaceutical substances and excipients. Accordingly, a range…
Bioresource Technology. 2013 Sep
High-level production of calcium malate from glucose by Penicillium sclerotiorum K302.
In this study, after screening of 9 fungal strains for their ability to produce calcium malate, it was found that Penicillium sclerotiorum K302 among them could produce high-level of calcium malate. Under the optimal conditions, the titer of calcium malate in the supernatant was 88.6 g/l at flask level. During 10-l fermentation, the titer of…
Journal of Dairy Science. 2019 Jan
Calcium lactate as an attractive compound to partly replace salt in blue-veined cheese.
In addition to their high sodium content, cheeses are thought to induce an acid load to the body, which is associated with deleterious effects on consumers’ health. Our objective was to explore the use of alkalinizing salts in partial substitution of NaCl to reduce both the sodium content and the acid-forming potential of cheese, without…
Environmental Toxicology and Pharmacology. 2015 Jan