Synonyms: Blue Vitriol, Copper(II) sulfate pentahydrate, Sulfuric acid, copper(II) salt (1:1) pentahydrate, Copper II sulphate 5-hydrate
Cupric Sulfate Pentahydrate USP/EP/GB Low HM Crystals can be used as a dietary ingredient and as a nutrient. Copper aids in the absorption of iron, in the formation of red blood cells and the proper bone formation and maintenance. Product specifications, SDSs and certifications are available under Additional Information.
Mineral Content (For formulation guidance/Not a specification)
Cu: 25.0% - 25.6%
Containers
55 lb/25 kg carton
Storage
Store in a clean, dry warehouse in the original unopened containers. The product may agglomerate in storage. It may be gently deagglomerated and screened prior to use.
The trace element copper is vital to the healthy functioning of organisms. Copper is used in a multitude of cellular activities including respiration, angiogenesis, and immune responses. Like other metals, copper homeostasis is a tightly regulated process. Copper is transported from dietary intake through the serum and into cells via a variety of transporters. There… Read Abstract
The essential trace metals iron, zinc, and copper play important roles both in retinal physiology and disease. They are involved in various retinal functions such as phototransduction, the visual cycle, and the process of neurotransmission, being tightly bound to proteins and other molecules to regulate their structure and/or function or as unbound free metal ions.… Read Abstract
The BRAF kinase is mutated, typically Val 600→Glu (V600E), to induce an active oncogenic state in a large fraction of melanomas, thyroid cancers, hairy cell leukaemias and, to a smaller extent, a wide spectrum of other cancers. BRAF(V600E) phosphorylates and activates the MEK1 and MEK2 kinases, which in turn phosphorylate and activate the ERK1 and… Read Abstract
Copper-ionophores that elevate intracellular bioavailable copper display significant therapeutic utility against prostate cancer cells in vitro and in TRAMP (Transgenic Adenocarcinoma of Mouse Prostate) mice. However, the pharmacological basis for their anticancer activity remains unclear, despite impending clinical trails. Herein we show that intracellular copper levels in prostate cancer, evaluated in vitro and across disease… Read Abstract